What time is the Cubs vs Padres game on April 27, and how can I watch it?

How to Watch

The game airs on Marquee Sports Network and streams on Peacock with the Padres broadcast, which requires a subscription. MLB.com's live streaming page also provides access to the game.

Matchup Details

Matthew Boyd starts for the Cubs after returning from a biceps strain. The 35-year-old veteran has struck out 22 and walked just three through 14 innings this season. Randy Vásquez takes the mound for the Padres, riding a strong season with a 1.88 ERA and 2-0 record. Vásquez recently threw seven shutout innings against the Rockies.

Series Context

This is a rematch of last year's NL Wild Card Series, which the Cubs won in three games. Both teams are off to strong starts in 2026, with the Cubs at 17-11 and the Padres at 18-9. The teams will play three games at Petco Park, with Game 2 on Tuesday at 8:40 p.m. CT and Game 3 on Wednesday at 1:10 p.m. CT.

Team Forms

The Cubs had won 10 straight before losing their last two games at Dodger Stadium. They have a plus-31 run differential, fourth best in the majors. The Padres won six straight series before splitting with Arizona in Mexico City. Their plus-12 run differential ranks seventh in the majors, but their 18-9 record is third best overall.